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E-mail: sykim415@daewoong.co.kr
¸¸¼ºÅëÁõ, ƯÈ÷ neuropathic painÀÇ Ä¡·áÁ¦ °³¹ßÀº °è¼Ó ½ÇÆи¦ °ÅµìÇÏ°í ÀÖ´Ù. ÀÌ°ÍÀº painÀÇ »ý¹°ÇÐÀûÀÎ ±â´ÉÀÌ ´Ü¼øÀÌ neuron¿¡ ÀÇÁ¸ÀûÀÌÁö ¾Ê°í º¸´Ù º¹ÀâÇϱ⠶§¹®ÀÌ´Ù. Pain°ú »óÈ£ÀÛ¿ëÇÏ´Â ¸é¿ª°èÀÇ ¿ªÇÒ¿¡ ´ëÇÏ¿© Á» ´õ ¾Ë¾Æ¾ß ÇÒ Çʿ伺Àº ¿©±â¿¡ ÀÖ´Ù. ½Å°æÀÇ ÈïºÐ¼ºÀº neurons¿¡¼ ºÐºñµÈ neurotransmitter »Ó ¾Æ´Ï¶ó, CNS¿¡ Á¸ÀçÇÏ´Â microglia, astrocyte, T cells ¿¡¼ ºÐºñµÇ´Â immune mediator¿¡ ÀÇÇؼ Áõ°¡ÇÑ´Ù. Neuron°ú ¸é¿ª°è¸¦ µ¿½Ã¿¡ °í·ÁÇØ¾ß ¸¸¼ºÅëÁõ¿¡ ´ëÇÑ »õ·Î¿î ½Å¾à°³¹ß °¡´É¼ºÀÌ ³ô¾ÆÁú °ÍÀÌ´Ù.
(ÀüüÀбâ´Â ÷ºÎÇÑ PDFÆÄÀÏÀ» ÂüÁ¶Çϱ⠹ٶø´Ï´Ù.)
Key Words: pain, microglia, neuropathic pain, astrocyte, cytokine
ÀÚ·áÃâó: http://www.ibric.org/myboard/read.php?Board=report&id=2517#
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